With great power comes great immunogenicity.  Learn about the ins and outs of immunotherapy–its indications, its power, and its adverse effects–in this episode with Dr. Christian Cable, hematologist/oncologist and medical educator extraordinaire.  We learn a riveting history of immunotherapy and about how checkpoint inhibitors work, as well as the best practices for identifying downstream effects of checkpoint inhibitors and their immune system activation (it’s all about the -Itis!). 

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Show Segments




Intro
What is Immunotherapy?
A History Lesson
Immune Checkpoint Inhibitors (ICIs) 
Immune Related Adverse Events (irAEs) 
Endocrine complications of checkpoint inhibitors
Rheumatologic complications of checkpoint inhibitors 
Considerations before starting checkpoint inhibitors (and what labs to check) 
Diagnosing and Managing irAEs 
Common post-irAE questions 
New Kids on the Block: CAR-T 
Take Home Points 



Credits




Written and Produced by: Nora Taranto MD
Hosted by: Molly Heublein MD; Nora Taranto MD; Paul Williams MD, FACP  
Guests: Christian Cable MD 
Show Notes: Nora Taranto MD 
Cover Art: Andrea Perdigão
Infographics: Andrea Perdigão
Reviewer: Emi Okamoto MD, FACP 
Production team: Pod Paste


Sponsor: Southern California Permanente Medical Group

Learn more or apply at scpmgphysiciancareers.com




Sponsor: Locumstory
Visit locumstory.com to learn more about locums. 

Full transcript HERE 

The Curbsiders are partnering with VCU Health Continuing Education to offer FREE continuing education credits for physicians and other healthcare professionals. Visit curbsiders.vcuhealth.org and search for this episode to claim credit

#342 Checkpoint Inhibitors: The power, and adverse effects, of immunotherapy (ACP 2022)

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